The 2-Minute Rule for cees dekker

The 2-Minute Rule for cees dekker

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Working with solitary-molecule optical and AFM imaging and power-spectroscopy techniques, we search for to unravel the mechanistic facets of the construction and dynamics of chromosomes. Our research passions contain:

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I can hardly envision how I, as being a geneticist, would have the ability to discover fundamental physics, let alone contend at the best. How did you go about this?

Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever structure in 2005. (nl)

SMC complexes can move Bodily roadblocks bigger than their ring size, indicating a nontopological system for DNA loop extrusion

Many similar developments adopted, in which our group recognized diverse transistor variants including single-electron transistors at home temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled a number of transistors into tiny evidence-of-theory Digital circuits.

Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in gray, the rim of your pore is highlighted in red, as well as a 3D rendering with the movement of the DNA rod is displayed.

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Really neat, but that wasn’t truly wherever my interest lay. I wished to pioneer And that i experienced the feeling that was no more probable, because the most exciting essential insights experienced presently been uncovered. But my subject experienced developed several enjoyable new applications to measure personal molecules. I made a decision which i needed to use this to biology, to take a look at it from the Bodily standpoint.’

‘The concept that There may be this kind of thing like a starting, a major bang, is already an interesting signpost to contemplate that there was a creator. But additional frequently, and on the basis of pure rationality, I also arrive at a Christian interpretation of actuality. An atheistic worldview is actually a naturalistic worldview: basically, you will discover only atoms and purely natural forces that we can measure.

‘That considerations the artificial cell, as Component of the Dutch BaSyC initiative. Craig Venter looked best-down in Those people days and discovered about 5 hundred genes which have been minimally necessary for just a working mobile. We wish to look bottom-up: how can we shift from a number of molecules to an entire biological technique?

2005, discovery of the mechanism of DNA uncoiling by topoisomerase cees dekker enzymes; discovery of extensive-assortment conformational changes in Mre11/DNA fix complexes; and to start with power measurements over a DNA molecule in a nanopore

‘I am driven by surprise and inquiries. On a cloth amount I locate solutions in physics, but I practical experience my deepest contentment with God. That religion also drives my science and how I cope with men and women.